Detection of Airway Obstruction in Exercise-Induced Asthma Observations

In most studies, the workload is reported as treadmill speed, the angle of inclination (or percentage of grade), and length of the exercise period. It has been shown that the external work performed on a treadmill also depends on body weight. Thus, to obtain more uniform and comparable data in the period after exercise, the workload expressed in watts was standardized per kilogram of body weight. Mild to moderate workloads requiring only a fast walk

Tagged: airway obstruction , Exercise-induced Asthma , heart rate , spirometry

Detection of Airway Obstruction in Exercise-Induced Asthma Outcomes

Heart Rate Response All patients increased their heart rates to 40-55 percent of predicted maximum heart rate during Wl and to 60-75 percent of predicted maximum heart rate during W2. In nearly all patients heart rates reached the steady state levels within three minutes; but in a few cases continuous increase in heart rates was observed, and by the end of the exercise, reached nearly 200 beats per minute. No extrasystoles or other arrhythmias were

Tagged: airway obstruction , Exercise-induced Asthma , heart rate , spirometry

Detection of Airway Obstruction in Exercise-Induced Asthma

Increased airway obstruction following exercise has frequently been observed in asthmatic patients. Different parameters such as forced expiratory volume in one second (FEV1), peak expiratory flow rate (PEFR), airway resistance (Raw), and specific airway conductance (SG.w)e have been used as indices of airway obstruction. Some authors have commented on the value of the stethoscope or the patients’ dyspnea in determining airway obstruction. The failure to establish a more accurate definition of exercise-induced asthma (EIA) can be partially

Tagged: airway obstruction , Exercise-induced Asthma , heart rate , spirometry

Disscusion about Conscious Perception of Bronchospasm as a Protective Phenomenon in Asthma

Previous publications on this topic: Conscious Perception of Bronchospasm as a Protective Phenomenon in Asthma Results of Conscious Perception of Bronchospasm as a Protective Phenomenon in Asthma Both neural and chemically mediated events contribute to the ventilatory responses seen when external loads are added to a subject’s breathing. The responses to internally loaded breathing cannot yet be studied in such a pure form. Thus, in our attempts to quantify the relationships between an internally added load and a subject’s awareness of the load, a number of compromises were accepted. The subjects were part of a well-motivated group

Tagged: breathing , chronic asthma , lung capacity , pulmonary dysfunction , pulmonary function

Results of Conscious Perception of Bronchospasm as a Protective Phenomenon in Asthma

Table 1 represents comparisons for the following indices of pulmonary function: total lung capacity (TLC), FRC, RV, FEVi, Raw, Vmax50 (uncorrected for lung volume), and V/V25-75. Comparisons were made in the following fashion. Consider the values of Raw for subject 1. On the first occasion listed, subject 1 was asymptomatic, the Raw being 76 percent of predicted. A change of 127 percent from that baseline level was seen when symptoms first became apparent. On the second occasion listed,

Tagged: breathing , chronic asthma , lung capacity , pulmonary dysfunction , pulmonary function

Conscious Perception of Bronchospasm as a Protective Phenomenon in Asthma

It has been commonly accepted but poorly documented that in the presence of chronic asthma, patients may become adapted to the presence of their pulmonary dysfunction. They may, for instance, remain asymptomatic but taper their activities to a lower level; their degree of pulmonary dysfunction might possibly be grossly underestimated and their therapy less than optimal. In keeping with this apparent blunting of perceptive ability with longstanding dysfunction, one might expect the perception of further

Tagged: breathing , chronic asthma , lung capacity , pulmonary dysfunction , pulmonary function

Discussion about Corticosteroid in Asthma for Exercise-Induced Bronchoconstriction and Sputum Eosinophils Results

Read details in previous publications: Introduction: “ Corticosteroid in Asthma for Exercise-Induced Bronchoconstriction and Sputum Eosinophils “ Results: “ Corticosteroid in Asthma for Exercise-Induced Bronchoconstriction and Sputum Eosinophils Results “ In steroid-naive asthmatic subjects with EIB, we demonstrated that 40% had elevated (> 5%) baseline sputum eosinophil percentage counts. These subjects had a greater fall in FEV1 following a standardized exercise challenge. Sputum eosinophil percentage was significantly correlated to and was an independent predictor of EIB severity. Treatment with low and high doses of ciclesonide resulted in significant reduction in �V1 fall postexercise at

Tagged: exercise-induced bronchoconstriction , inhaled corticosteroids , sputum eosinophils , steroid responsiveness

Corticosteroid in Asthma for Exercise-Induced Bronchoconstriction and Sputum Eosinophils Results

Introduction: Read more in previous publication “ Corticosteroid in Asthma for Exercise-Induced Bronchoconstriction and Sputum Eosinophils “. Twenty-six subjects (16 male subject) were enrolled into the study. The ratio of enrolled to screened subjects was 1:3 (Fig 1). One subject was excluded from all analyses due to inadequate sputum sample production, one subject did not crossover due to insufficient �V1 fall after washout, and another subject missed one visit due to a musculoskeletal injury. All data were included up to the time of study withdrawal.

Tagged: exercise-induced bronchoconstriction , inhaled corticosteroids , sputum eosinophils , steroid responsiveness

Corticosteroid in Asthma for Exercise-Induced Bronchoconstriction and Sputum Eosinophils

Fosinophils may be important in the pathophysiology of exercise-induced bronchoconstriction (EIB) and the response to therapy in patients with chronic asthma ( read more ). In vitro studies have demonstrated that eosinophils generate and release cysteinyl leu-kotrienes when subjected to a hyperosmolar stimulus, which is an important condition that provokes EIB. Cysteinyl leukotrienes are potent bronchocon-strictor mediators that are implicated in EIB. Furthermore, the presence and severity of EIB is significantly correlated to eosinophil levels measured in

Tagged: exercise-induced bronchoconstriction , inhaled corticosteroids , sputum eosinophils , steroid responsiveness

Results and Disscusion of Wheezing in Acute Asthma Quantitation

To learn this research materials and methods follow this link . Twenty patients, with a mean age of 43 years, were studied. Eighteen of the 20 were female. All 20 had audible wheezing before treatment; 12 of them still had some wheeze after treatment. All patients showed improvement in their FEV1 the mean value for the group rose from 1.15±0.39 L (mean±SD) before treatment to 1.49 ±0.43 L after treatment. Peak expiratory flow rates improved from 150

Tagged: asthma , pulmonary function , wheezing