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Roentgenographic Abnormalities in Children Hospitalized for Asthma Deliberation

The total incidence of roentgenographic abnormalities (64.1 percent) in our series of children who were hospitalized for status asthmaticus is similar to previously reported observations. The most common abnormality was hyperinflation, found in 35.9 percent of those studied roentgenographically. Of the 35 patients (27.3 percent) with opacifications on their chest x-ray film, only six (4.7 percent) were suggestive of pneumonia. This is comparable to the data of Eggleston et al who reported pneumonitis in 4.5

Roentgenographic Abnormalities in Children Hospitalized for Asthma Outcomes

Of the 129 children admitted to the hospital in status asthmaticus during the study period, 128 had chest roentgenograms. Eighty-four (65.6 percent) of the patients had been admitted previously for asthma, while 32 ( 24.8 percent) had previously been treated only as outpatients. The remaining patients had never wheezed before the episode which precipitated admission. Three patients were admitted to the intensive care unit; the remainder were admitted to a regular pediatric floor. The episodes

Methods of Roentgenographic Abnormalities in Children Hospitalized for Asthma

Abnormal chest roentgenograms have been reported in 43 to 76 percent of children who are hospitalized with asthma ( read everything about Childhood Asthma ). When the roentgenograms reported to show only “hyperaeration” or “emphysematous changes” are excluded, the frequency of abnormal findings is still one in four. This has resulted in the recommendation that a chest x-ray examination be a part of the evaluation of any patient admitted to the hospital with asthma. The purpose of this investigation was

Absence of Relationships Between Tuberculin Responses and Development of Adult Asthma Observations

This study demonstrates that the magnitude of tuberculin response was similar among asthma-rhinitis and healthy, atopic and nonatopic Chinese adults in the Guangdong area. There was no association between tuberculin response, presence of BCG scars, and asthma and rhinitis as well as atopy. These results were consistent in both the univariate and multivariate analyses. We employed allergen SPT, serum-total, and serum-specific IgE levels as markers to indicate atopic status of our study subjects. These markers

Absence of Relationships Between Tuberculin Responses and Development of Adult Asthma Outcomes

The characteristics of the study and healthy control groups are presented in Table 1. By strictly adhering to the protocol of the study, the distribution of age and gender of subjects in both groups was similar. A significant higher proportion of asthma-rhinitis subjects had previous (45.8% vs 4.1%) and present (50.5% vs 2.7%) eczema as compared with healthy subjects. There were no differences between the two groups with regards to the percentage of subjects with

Absence of Relationships Between Tuberculin Responses and Development of Adult Asthma

The prevalence of allergic rhinitis and asthma has increased in many countries in recent decades. The reason for this increase is not clear but has been largely attributed to environmental factors such as exposure to aerial pollutants and early life events, including the degree of exposure to infectious agents that might affect IgE production. Extensive evidence suggests that the decrease of bacterial and viral infection because of the improvement of living standard and reinforcement of

Sputum Induction and Bronchoscopy for Assessment of Ozone-Induced Airway Inflammation in Asthma Observations

In this study, we used a model of irritant-induced nonspecific inflammation to compare these two methods of sampling RTLF. Inhaled O3 at high ambient concentrations can induce the recruitment of neutrophils into the airway lumen. This has been demonstrated by increases in both the concentration of polymorphonuclear neutrophils and the %PMNs in RTLF samples obtained by bronchoscopy as well as by SI. In our study, O3 exposure increased the %PMNs in BAL fluid and the

Sputum Induction and Bronchoscopy for Assessment of Ozone-Induced Airway Inflammation in Asthma Outcomes

Spirometry The mean (± SD) values of the spirometry indexes are shown in Table 2. The preexposure FEVj values for all subjects were similar in all arms of the study. Across FA exposures, there was a slight increase in FEV1. Across O3 exposures, there was a significant decrease in FEV1. The post-FA exposure FEV1 values for all subjects were similar in the SI and bronchoscopy arms of the study, as they were after O3. FVC

Sputum Induction and Bronchoscopy for Assessment of Ozone-Induced Airway Inflammation in Asthma Research

Study Design The study had a randomized crossover design. Subjects were exposed either to O3 or FA for 4 h followed by either bronchoscopy or SI 18 h later. Subjects then underwent the alternate exposure (O3 or FA) followed by the same method of airway lining fluid sampling. In the crossover part of the study, subjects repeated the same exposure protocol with the alternate method of airway Lining fluid sampling. Subjects Subjects were initially recruited

Sputum Induction and Bronchoscopy for Assessment of Ozone-Induced Airway Inflammation in Asthma

Studies of human respiratory tract inflammation have traditionally relied on the analysis of samples of airway and alveolar lining fluid and bronchial tissue obtained by bronchoscopy. Although the analysis of these samples has contributed much to our current understanding of various pulmonary disease processes, bronchoscopy is invasive, technically difficult, and not always acceptable to volunteer subjects. Sputum induction (SI) has been demonstrated to be a noninvasive alternate method of assessing airway inflammation that is reproducible, valid, and